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Clinical trials on female volunteers demonstrated greater immune response from a vaginal vaginal vs anal containing cholera vaccine than an orally administered cholera vaccine. During unprotected vaginal intercourse, the man is being exposed to vaginal secretions, and possibly menstrual blood as well. If you're not doing it all the time, anal is a good way to change things up.

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Exploring the unconventional routes — rectal and vaginal dosage formulations

Ask the Experts About. Which is what a group of British researchers did recently for the age-old question: This route can also be useful for delivering drugs to prevent pre- and post-operative systemic infections.

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What Does Vaginal Sex Feel Like? 13 Men Compare It To Anal Sex

The rectum and vagina are the drug delivery routes of choice for a range of therapeutic indications. Unexplored territory can have a powerful grasp. Liquid formulations that turn to gel once inserted into the rectum can allow easier administration and positioning than conventional suppositories and can prevent dosage form leakage, which is common with rectal suspensions and enemas.

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